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Literature summary for 5.3.3.1 extracted from

  • Weintraub, H.; Vincent, F.; Baulieu, E.E.; Alfsen, A.
    Interaction of steroids with Pseudomonas testosteroni 3-oxosteroid DELTA4-DELTA5 isomerase (1977), Biochemistry, 16, 5045-5053.
    View publication on PubMed
Search for more literature for 5.3.3.1

Inhibitors

Inhibitors Comment Organism Structure
3-Deoxyestradiol mixed noncompetitive Comamonas testosteroni
4,4'-Dihydroxy-2',7'-dimethyl-7-ethyl-trans-stilbene noncompetitive Comamonas testosteroni
4,4'-Dihydroxy-2',7-dimethyl-7'-ethyl-trans-stilbene competitive Comamonas testosteroni
coumestrol mixed noncompetitive Comamonas testosteroni
diethylstilbestrol competitive Comamonas testosteroni
estradiol competitive Comamonas testosteroni
estrone and derivatives, noncompetitive Comamonas testosteroni
additional information overview: interaction of the enzyme with steroids Comamonas testosteroni

Organism

Organism UniProt Comment Textmining
Comamonas testosteroni
-
-
-

Reaction

Reaction Comment Organism Reaction ID
a 3-oxo-DELTA5-steroid = a 3-oxo-DELTA4-steroid "flip-flop" mechanism may be involved Comamonas testosteroni
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-Androstene-3,17-dione
-
 Comamonas testosteroni 4-Androstene-3,17-dione
-
 ?