Literature summary for 5.3.1.9 extracted from

Solomons, J.T.G.; Zimmerly, E.M.; Burns, S.; Krishnamurthy, N.; Swan, M.K.; Krings, S.; Muirhead, H.; Chirgwin, J.; Davies, C.
The crystal structure of mouse phosphoglucose isomerase at 1.6 A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening (2004), J. Mol. Biol., 342, 847-860.

Search for more literature for 5.3.1.9

Crystallization (Commentary)

Crystallization (Comment)	Organism
native enzyme and in complex with glucose 6-phosphate or erythrose 4-phosphate	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P06745	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
alpha-D-glucose 6-phosphate = beta-D-fructofuranose 6-phosphate	push-pull mechanism of ring opening in which H388 breaks the O5-C1 bond by donating a proton, and simultaneously, K518 abstracts a proton from the C1 hydroxyl group	Mus musculus	a

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)