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Literature summary for 5.2.1.8 extracted from

  • St-Denis, N.A.; Bailey, M.L.; Parker, E.L.; Vilk, G.; Litchfield, D.W.
    Localization of phosphorylated CK2alpha to the mitotic spindle requires the peptidyl-prolyl isomerase Pin1 (2011), J. Cell Sci., 124, 2341-2348.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
C113S catalytically inactive Homo sapiens
R68/69A catalytically inactive Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
spindle
-
Homo sapiens 5819
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
peptidyl-prolyl isomerase
-
Homo sapiens
Pin1
-
Homo sapiens
PPIase
-
Homo sapiens

General Information

General Information Comment Organism
malfunction knockdown of Pin1 does not prevent CK2alpha phosphorylation Homo sapiens
physiological function peptidyl-prolyl isomerase Pin1 is required for CK2alpha mitotic spindle localization. Pin1 protects CK2alpha from dephosphorylation in vivo Homo sapiens