Protein Variants | Comment | Organism |
---|---|---|
additional information | disruption of the fkpA gene results in a 47.9fold and 32.1fold decrease in thermotolerance in 5-h and 24-h CS cells, respectively, compared to the parental strain | Salmonella enterica subsp. enterica serovar Typhimurium |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
periplasm | - |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Salmonella enterica subsp. enterica serovar Typhimurium | - |
strains C5 and SL1344, genes surA and fkpA. SurA can functionally compensate for the absence of FkpA, but when SurA is missing, or especially when both SurA and FkpA are missing, the ability of cells to survive or recover from prolonged periods of C-starvation is significantly impaired | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | carbon-starved cells | Salmonella enterica subsp. enterica serovar Typhimurium | - |
Synonyms | Comment | Organism |
---|---|---|
FkpA | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
peptidyl-prolyl isomerase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
SurA | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
Organism | Comment | Expression |
---|---|---|
Salmonella enterica subsp. enterica serovar Typhimurium | genes surA and fkpA are not carbon energy source-starvation inducible, and their expression during C-starvation does not appear to be sigmaE-dependent, overview | additional information |
General Information | Comment | Organism |
---|---|---|
additional information | SurA and FkpA are not involved in the starvation-stress response, SSR. Genes surA and fkpA appear to be dispensable for the cross-resistance of carbon-starved cells to oxidative stress | Salmonella enterica subsp. enterica serovar Typhimurium |
physiological function | SurA may function to repair, or prevent damage to, the outer membrane upon exposure to PmB and may consequently limit damage to the inner-membrane | Salmonella enterica subsp. enterica serovar Typhimurium |