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Literature summary for 5.2.1.8 extracted from
- The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9 (2001), J. Mol. Biol., 312, 675-685.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | peptidylprolyl isomerase Pin1 interacts with Cdk9-phosphorylated hSpt5. Cdk9 dependent phosphorylation of Rpb1 and hSpt5 followed by Pin1 interaction might contribute to the regulation of transcription, pre-mRNA maturation and the dynamics of proteins in interphase and mitosis | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | peptidylprolyl isomerase Pin1 interacts with Cdk9-phosphorylated hSpt5. Cdk9 dependent phosphorylation of Rpb1 and hSpt5 followed by Pin1 interaction might contribute to the regulation of transcription, pre-mRNA maturation and the dynamics of proteins in interphase and mitosis | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Pin1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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