Inhibitors | Comment | Organism | Structure |
---|---|---|---|
lactalbumin | reduced and carboxymethylated, strong inhibition by the permanently unfolded protein | Bacillus subtilis | |
RNase T1 | reduced and carboxymethylated form of the P39A variant, strong inhibition by the permanently unfolded protein | Bacillus subtilis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00045 | - |
RNase T1 | trigger factor | Bacillus subtilis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
17600 | - |
cyclophilin | Bacillus subtilis |
47300 | - |
trigger factor | Bacillus subtilis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bacillus subtilis | only two enzymes, the cyclophilin and the trigger factor, contribute to the peptidylprolyl isomerase activity. The prolyl isomerases become essential for growth under starvation conditions | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | only two enzymes, the cyclophilin and the trigger factor, contribute to the peptidylprolyl isomerase activity | Bacillus subtilis | ? | - |
? | |
additional information | only two enzymes, the cyclophilin and the trigger factor, contribute to the peptidylprolyl isomerase activity. The prolyl isomerases become essential for growth under starvation conditions | Bacillus subtilis | ? | - |
? | |
RNAse T1 | reduced and carboxymethylated form of the S54G/P55N variant of RNAse T1. In the native state the Rnase T1 contains a single prolyl bond Tyr38-Pro39. Of all reduced and carboxymethylated RNAse T1 molecules, 85% fold in a monophasic and reversible reaction, which is limited in rate by the slow trans to cis isomerization at Pro39 | Bacillus subtilis | ? | - |
? | |
succinyl-Ala-Phe-(trans)-Pro-Phe-4-nitroanilide | - |
Bacillus subtilis | succinyl-Ala-Phe-(cis)-Pro-Phe-4-nitroanilide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cyclophilin | - |
Bacillus subtilis |
trigger factor | - |
Bacillus subtilis |