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Literature summary for 5.2.1.8 extracted from

  • Compton, L.A.; Davis, J.M.; MacDonald, J.R.; Bächinger, H.P.
    Structural and functional characterization of Escherichia coli peptidyl-prolyl cis-trans isomerases (1992), Eur. J. Biochem., 206, 927-934.
    View publication on PubMed
Search for more literature for 5.2.1.8

Inhibitors

Inhibitors Comment Organism Structure
cyclosporin A
-
 Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm anionic enzyme form. Antibodies against the periplasmic enzyme form do not recognize the cytoplasmic enzyme, indicating significant differences in epitopes between the two forms Escherichia coli 5737
-
periplasm cationic enzyme form Escherichia coli
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
18137
-
 x * 18137, cationic enzyme form, calculation from amino acid sequence Escherichia coli
18181
-
 x * 18181, calculation from amino acid sequence Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information catalyzes the refolding of thermally denatured type III collagen Escherichia coli ?
-
 ?
succinyl-Ala-Ala-(cis)-Pro-Phe 4-methylcoumarin 7-amide
-
 Escherichia coli succinyl-Ala-Ala-(trans)-Pro-Phe + 7-amino-4-methylcoumarin
-
 ?
succinyl-Ala-Ala-Pro-Phe 4-nitroanilide
-
 Escherichia coli succinyl-Ala-Ala-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Glu-(cis)-Pro-Phe 4-nitroanilide
-
 Escherichia coli Succinyl-Ala-Glu-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Gly-(cis)-Pro-Phe 4-nitroanilide
-
 Escherichia coli Succinyl-Ala-Gly-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-His-(cis)-Pro-Phe 4-nitroanilide
-
 Escherichia coli Succinyl-Ala-His-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Leu-(cis)-Pro-Phe 4-nitroanilide
-
 Escherichia coli Succinyl-Ala-Leu-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Lys-(cis)-Pro-Phe 4-nitroanilide
-
 Escherichia coli Succinyl-Ala-Lys-(trans)-Pro-Phe 4-nitroanilide
-
 ?
Succinyl-Ala-Phe-(cis)-Pro-Phe 4-nitroanilide
-
 Escherichia coli Succinyl-Ala-Phe-(trans)-Pro-Phe 4-nitroanilide
-
 ?

Subunits

Subunits Comment Organism
? x * 18181, calculation from amino acid sequence Escherichia coli
? x * 18137, cationic enzyme form, calculation from amino acid sequence Escherichia coli

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
56
-
 30 min, cationic enzyme form, no loss of activity Escherichia coli