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BRENDA support

Literature summary for 5.1.3.4 extracted from

  • Deupree, J.D.; Wood, W.A.
    L-Ribulose 5-phosphate 4-epimerase from Aerobacter aerogenes. Evidence for a role of divalent metal ions in the epimerization reaction (1972), J. Biol. Chem., 247, 3093-3097.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2,3-dimercapto-1-propanol
-
Klebsiella aerogenes
8-Hydroxyquinoline sulfonate
-
Klebsiella aerogenes
EDTA reactivated by addition of divalent metal ion in decreasing order: Mn2+, Co2+, Ni2+, Ca2+, Zn2+, Mg2+ Klebsiella aerogenes
mercaptoethanol
-
Klebsiella aerogenes

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ divalent metal ion required. Reactivated by addition of divalent metal ion in decreasing order: Mn2+, Co2+, Ni2+, Ca2+, Zn2+, Mg2+ Klebsiella aerogenes
Co2+ divalent metal ion required. Reactivated by addition of divalent metal ion in decreasing order: Mn2+, Co2+, Ni2+, Ca2+, Zn2+, Mg2+ Klebsiella aerogenes
Mg2+ divalent metal ion required. Reactivated by addition of divalent metal ion in decreasing order: Mn2+, Co2+, Ni2+, Ca2+, Zn2+, Mg2+ Klebsiella aerogenes
Mn2+ reactivated after EDTA treatment by addition of divalent metal ion in decreasing order: Mn2+, Co2+, Ni2+, Ca2+, Zn2+, Mg2+ Klebsiella aerogenes
Mn2+ in presence of the optimal concentration of Mn2+ the specific activity is 5times greater than that displayed by the crystalline enzyme as isolated and assayed in absence of added metal Klebsiella aerogenes
Ni2+ divalent metal ion required. Reactivated by addition of divalent metal ion in decreasing order: Mn2+, Co2+, Ni2+, Ca2+, Zn2+, Mg2+ Klebsiella aerogenes
Zn2+ divalent metal ion required. Reactivated by addition of divalent metal ion in decreasing order: Mn2+, Co2+, Ni2+, Ca2+, Zn2+, Mg2+ Klebsiella aerogenes

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ribulose 5-phosphate
-
Klebsiella aerogenes D-Xylulose 5-phosphate
-
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