Application | Comment | Organism |
---|---|---|
medicine | Galactosylation of one or more glycoprotein(s), most likely in the endosomal/lysosomal system, is essential for the survival of bloodstream form Trypanosoma brucei. GalE-encoded epimerase and the downstream UDP-Gal transporters and UDP-Gal-dependent glycosyltransferases may be exploitable as drug targets. | Trypanosoma brucei |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-alpha-D-glucose | Trypanosoma brucei | Galactose metabolism is essential for the survival of Trypanosoma brucei, the etiological agent of African sleeping sickness. | UDP-alpha-D-galactose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-alpha-D-glucose | Galactose metabolism is essential for the survival of Trypanosoma brucei, the etiological agent of African sleeping sickness. | Trypanosoma brucei | UDP-alpha-D-galactose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
UDP-glucose 4'-epimerase | - |
Trypanosoma brucei |