Literature summary for 5.1.1.3 extracted from

de Almeida Leone, P.; Carroll, A.R.; Towerzey, L.; King, G.; McArdle, B.M.; Kern, G.; Fisher, S.; Hooper, J.N.; Quinn, R.J.
Exiguaquinol: a novel pentacyclic hydroquinone from Neopetrosia exigua that inhibits Helicobacter pylori MurI (2008), Org. Lett., 10, 2585-2588.

Search for more literature for 5.1.1.3

Inhibitors

Inhibitors	Comment	Organism	Structure
exiguaquinol	pentacyclic hydroquinone from Neopetrosia exigua, protein-ligand modeling	Helicobacter pylori

Organism

Organism	UniProt	Comment	Textmining
Helicobacter pylori	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-glutamate	-	Helicobacter pylori	L-glutamate	-	r
D-serine-O-sulfate	-	Helicobacter pylori	L-serine-O-sulfate	-	r

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0044	-	substrate D-serine-O-sulfate	Helicobacter pylori	exiguaquinol
0.361	-	substrate D-glutamate	Helicobacter pylori	exiguaquinol

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)