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Literature summary for 4.4.1.5 extracted from
- Distinct subcellular localization in the cytosol and apicoplast, unexpected dimerization and inhibition of Plasmodium falciparum glyoxalases (2010), Mol. Microbiol., 76, 92-103.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| curcumin | - |
Plasmodium falciparum |  |
| methyl gerfelin | - |
Plasmodium falciparum | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Plasmodium falciparum | 5829 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| methylglyoxal + glutathione | Plasmodium falciparum | - |
(R)-S-lactoylglutathione | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Plasmodium falciparum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| methylglyoxal + glutathione | - |
Plasmodium falciparum | (R)-S-lactoylglutathione | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GloI | - |
Plasmodium falciparum |
| glyoxalase I | - |
Plasmodium falciparum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| glutathione | - |
Plasmodium falciparum | |
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