Any feedback?
Literature summary for 4.4.1.5 extracted from
- The role of glyoxalase system in renal hypoxia (2010), Adv. Exp. Med. Biol., 662, 49-55.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Rattus norvegicus | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| methylglyoxal + glutathione | - |
Homo sapiens | (R)-S-lactoylglutathione | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glyoxalase I | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| glutathione | - |
Homo sapiens | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | glyoxalase I has renoprotective effects in renal hypoxia such as ischemia/reperfusion injury via a reduction in cytotoxic methylglyoxal level in tubular cell | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
