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Literature summary for 4.4.1.5 extracted from

  • Kitamura, Y.; Kawase, M.; Ohmori, S.
    Formate excretion in urine of rats fed dimethylaminoazobenzene-rich diets: the possibility of formate formation from D-lactate (2008), Acta Med. Okayama, 62, 193-203.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus glyoxalase I catalyzes the isomerization reaction of thiohemiacetal, which is formed nonenzymatically from methylglyoxal and glutathione ?
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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(SPF/VAF)-strain albino rats
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Source Tissue

Source Tissue Comment Organism Textmining
liver
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Rattus norvegicus
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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determined spectrophotometrically at 240 nm, glyoxalase I activities for 2-methyl-4-dimethylaminoazobenzene-fed rats (10 weeks fed) are 1.7times higher than that of control animals Rattus norvegicus
additional information
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determined spectrophotometrically at 240 nm, glyoxalase I activities for 3'-methyl-4-dimethylaminoazobenzene-fed rats (10 weeks fed) are 1.6times higher than that of control animals Rattus norvegicus
additional information
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determined spectrophotometrically at 240 nm, glyoxalase I activities for 4'-methyl-4-dimethylaminoazobenzene-fed rats (10 weeks fed) are 1.5times higher than that of control animals Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information glyoxalase I catalyzes the isomerization reaction of thiohemiacetal, which is formed nonenzymatically from methylglyoxal and glutathione Rattus norvegicus ?
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?

Synonyms

Synonyms Comment Organism
glyoxalase I
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Rattus norvegicus
lactoylglutathione lyase
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Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
glutathione
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Rattus norvegicus