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Literature summary for 4.4.1.5 extracted from

  • Allen, R.E.; Lo, T.W.C.; Thornalley, P.J.
    A simplified method for the purification of human red blood cell glyoxalase. I. Characteristics, immunoblotting, and inhibitor studies (1993), J. Protein Chem., 12, 111-119.
    View publication on PubMed
Search for more literature for 4.4.1.5

Inhibitors

Inhibitors Comment Organism Structure
GSH weak Homo sapiens
S-(4-nitrobenzyloxycarbonyl)glutathione
-
 Homo sapiens
S-p-bromobenzylglutathione competitive Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.192
-
 glutathione-methylglyoxal hemithioacetal
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
23000
-
 2 * 23000, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1830
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione-methylglyoxal hemithioacetal
-
 Homo sapiens (R)-S-lactoylglutathione
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 23000, SDS-PAGE Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1820
-
 glutathione-methylglyoxal hemithioacetal
-
 Homo sapiens