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Literature summary for 4.4.1.5 extracted from

  • Mannervik, B.; Aronsson, A.C.; Tibbelin, G.
    Glyoxalase I from human erythrocytes (1982), Methods Enzymol., 90, 535-541.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
S-p-bromobenzylglutathione
-
Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.04
-
Phenylglyoxal
-
Homo sapiens
0.13
-
methylglyoxal
-
Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
46000
-
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
3 isoenzymes
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1150
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + methylglyoxal
-
Homo sapiens S-lactoylglutathione
-
?
glutathione + phenylglyoxal
-
Homo sapiens S-mandeloylglutathione
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1070
-
Phenylglyoxal
-
Homo sapiens
1130
-
methylglyoxal
-
Homo sapiens