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Literature summary for 4.3.3.7 extracted from

  • Dobson, R.C.; Griffin, M.D.; Roberts, S.J.; Gerrard, J.A.
    Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate (2004), Biochimie, 86, 311-315.
    View publication on PubMed
Search for more literature for 4.3.3.7

Cloned(Commentary)

Cloned (Comment) Organism
-
 Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
(S)-lysine partial mixed inhibition with respect to its first substrate, pyruvate Escherichia coli

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.11
-
 (S)-aspartate 4-semialdehyde 30°C Escherichia coli
0.26
-
 pyruvate 30°C Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-aspartate 4-semialdehyde + pyruvate
-
 Escherichia coli dihydrodipicolinate + H2O
-
 ?

Synonyms

Synonyms Comment Organism
DHDPS
-
 Escherichia coli

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
124
-
 pyruvate 30°C Escherichia coli
124
-
 (S)-aspartate 4-semialdehyde 30°C Escherichia coli

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.32
-
 (S)-lysine versus (S)-aspartate 4-semialdehyde Escherichia coli
3.9
-
 (S)-lysine versus pyruvate Escherichia coli