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Literature summary for 4.3.2.2 extracted from
- Adenylosuccinate AMP-lyase (Neurospora crassa) (1978), Methods Enzymol., 11, 202-207.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 200000 | - |
- |
Neurospora crassa |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-(N-succino)-5-aminoimidazole-4-carboxamide ribonucleotide | Neurospora crassa | enzyme catalyzes two nonsequential reactions in purine biosynthesis | 5-aminoimidazole-4-carboxamide ribonucleotide + fumarate | - |
? |  |
| N6-(1,2-dicarboxyethyl)AMP | Neurospora crassa | terminal step in AMP biosynthesis | fumarate + AMP | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Neurospora crassa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Neurospora crassa |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Neurospora crassa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5-aminoimidazole | - |
Neurospora crassa | 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide + fumarate | - |
? | |
| 4-(N-succino)-5-aminoimidazole-4-carboxamide ribonucleotide | enzyme catalyzes two nonsequential reactions in purine biosynthesis | Neurospora crassa | 5-aminoimidazole-4-carboxamide ribonucleotide + fumarate | - |
? | |
| N6-(1,2-dicarboxyethyl)AMP | i.e. adenylosuccinate | Neurospora crassa | fumarate + AMP | - |
? | |
| N6-(1,2-dicarboxyethyl)AMP | terminal step in AMP biosynthesis | Neurospora crassa | fumarate + AMP | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| More | enzyme is composed of 6-8 identical subunits | Neurospora crassa |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.3 | - |
- |
Neurospora crassa |
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Release 2023.1 (January 2023)
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