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Literature summary for 4.3.1.19 extracted from

  • Burns, R.O.; Hofler, J.G.; Luginbuhl, G.H.
    Threonine deaminase from Salmonella typhimurium. Substrate-specific patterns of inhibition in an activator site-deficient form of the enzyme (1979), J. Biol. Chem., 254, 1074-1079.
    View publication on PubMed
Search for more literature for 4.3.1.19

Protein Variants

Protein Variants Comment Organism
additional information mutant with an activator site-deficient enzyme form, the Km for L-Thr is increased 4fold as compared with the wild type enzyme Salmonella enterica subsp. enterica serovar Typhimurium

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.5
-
 L-Thr wild type enzyme Salmonella enterica subsp. enterica serovar Typhimurium
19
-
 L-Thr mutant strain DU-21 Salmonella enterica subsp. enterica serovar Typhimurium
80
-
 L-Ser mutant strain DU-21 Salmonella enterica subsp. enterica serovar Typhimurium
90
-
 L-Ser wild type enzyme Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium
-
 mutant with an activator site-deficient enzyme form
-

Purification (Commentary)

Purification (Comment) Organism
mutant strain DU-21 with an activator site-deficient enzyme form Salmonella enterica subsp. enterica serovar Typhimurium

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
683
-
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ser
-
 Salmonella enterica subsp. enterica serovar Typhimurium pyruvate + NH3
-
 ?
L-threonine
-
 Salmonella enterica subsp. enterica serovar Typhimurium 2-oxobutanoate + NH3
-
 ?