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Literature summary for 4.2.99.18 extracted from

  • Harris, J.L.; Jakob, B.; Taucher-Scholz, G.; Dianov, G.L.; Becherel, O.J.; Lavin, M.F.
    Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage (2009), Hum. Mol. Genet., 18, 4102-4117.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA
-
Homo sapiens fragments of DNA
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?

Synonyms

Synonyms Comment Organism
APE1 also known as APEX, HAP1 and Ref1 Homo sapiens
apurinic endonuclease 1
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Homo sapiens

General Information

General Information Comment Organism
physiological function APE1 has a central role in the coordination of base excision repair Homo sapiens