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Literature summary for 4.2.99.18 extracted from

  • Al-Attar, A.; Gossage, L.; Fareed, K.R.; Shehata, M.; Mohammed, M.; Zaitoun, A.M.; Soomro, I.; Lobo, D.N.; Abbotts, R.; Chan, S.; Madhusudan, S.
    Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers (2010), Br. J. Cancer, 102, 704-709.
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine APE1 is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA Homo sapiens
-
 fragments of DNA
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gastroesophageal cancer cell
-
 Homo sapiens
-
ovarian cancer cell
-
 Homo sapiens
-
pancreatico-biliary cancer cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA
-
 Homo sapiens fragments of DNA
-
 ?

Synonyms

Synonyms Comment Organism
AP endonuclease
-
 Homo sapiens
APE1
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function APE1 is a key multifunctional protein involved in DNA base excision repair Homo sapiens