Application | Comment | Organism |
---|---|---|
medicine | downregulation of APE1 is found to sensitize tumor cells to chemotherapy with induction of apoptosis | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
P53 | after camptothecin treatment, p53 is a negative regulator of APE1 expression, APE1 promoter activity is repressed by wild-type p53, but not by mutant p53 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HCT-116 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
AP-endonuclease | - |
Homo sapiens |
APE1 | - |
Homo sapiens |
APE1/Ref-1 | - |
Homo sapiens |