Cloned (Comment) | Organism |
---|---|
Apn2 | Saccharomyces cerevisiae |
Protein Variants | Comment | Organism |
---|---|---|
additional information | deletion mutant delta369 and delta491, the C-terminal deletion does not affect the AP endonuclease activity, but the protein is defective in the removal of AP sites in vivo | Saccharomyces cerevisiae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NaCl | inhibition above 150 mM | Saccharomyces cerevisiae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
NaCl | 150 mM, higher concentrations inhibit | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA | Saccharomyces cerevisiae | - |
fragments of DNA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Apn2 | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA | - |
Saccharomyces cerevisiae | fragments of DNA | - |
? | |
DNA | catalyzes the hydrolysis of the 5'-phosphodiester bond at the abasic site | Saccharomyces cerevisiae | fragments of DNA | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | 8.8 | - |
Saccharomyces cerevisiae |