Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Triton X-100 | no stimulation | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Mus musculus | 5737 | - |
mitochondrion | - |
Mus musculus | 5739 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | stimulation | Mus musculus | |
KCl | enzyme form A: optimal activity in 20 mM NaCl or KCl, enzyme form B: more active without salt | Mus musculus | |
Mg2+ | stimulates | Mus musculus | |
Mg2+ | optimal concentration: 1-5 mM | Mus musculus | |
Mn2+ | stimulates | Mus musculus | |
NaCl | enzyme form A: optimal activity in 20 mM NaCl or KCl, enzyme form B: more active without salt | Mus musculus | |
Zn2+ | stimulation half as effective as with Mg2+ | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
61000 | - |
sedimentation data | Mus musculus |
65000 | - |
1 * 65000, SDS-PAGE | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA | Mus musculus | - |
fragments of DNA | - |
? | |
additional information | Mus musculus | role in eliminating damaged mitochondrial genomes from the gene pool | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
enzyme forms A and B | - |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MPC-11 cell | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
19 | - |
- |
Mus musculus |
Storage Stability | Organism |
---|---|
-80°C, pH 8.0, 1 mM EDTA, 0.05% Triton X-100, 0.5 mM dithiothreitol, 10 mM KCl, 3 months | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA | - |
Mus musculus | fragments of DNA | - |
? | |
DNA | supercoiled DNA | Mus musculus | fragments of DNA | - |
? | |
additional information | role in eliminating damaged mitochondrial genomes from the gene pool | Mus musculus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 65000, SDS-PAGE | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | 7.5 | enzyme form B | Mus musculus |
6.5 | 9 | enzyme form A | Mus musculus |