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Literature summary for 4.2.99.18 extracted from

  • Whisstock, J.C.; Romero, S.; Gurung, R.; Nandurkar, H.; Ooms, L.M.; Bottomley, S.P.; Mitchell, C.A.
    The inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis (2000), J. Biol. Chem., 275, 37055-37061.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
DNA Mammalia
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fragments of DNA
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?

Organism

Organism UniProt Comment Textmining
Mammalia
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DNA
-
Mammalia fragments of DNA
-
?
additional information inositol polyphosphate 5-phosphatase enzymes show high homology to AP endonucleases in regions that correspond to catalytic residues, they also share a similar mechanism of catalysis to the AP endonuclease consistent with other common functional similarities such as an absolute requirement for magnesium Mammalia ?
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?