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Literature summary for 4.2.3.4 extracted from

  • Moore, J.D.; Coggins, J.R.; Virden, R.; Hawkins, A.R.
    Efficient independent activity of a monomeric, monofunctional dehydroquinate synthase derived from the N-terminus of the pentafunctional AROM protein of Aspergillus nidulans (1994), Biochem. J., 301, 297-304.
    View publication on PubMedView publication on EuropePMC
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Inhibitors

Inhibitors Comment Organism Structure
diethyl dicarbonate
-
 Aspergillus nidulans
EDTA
-
 Aspergillus nidulans

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0022
-
 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
-
 Aspergillus nidulans
0.003
-
 NAD+ cofactor NAD+ Aspergillus nidulans

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+
-
 Aspergillus nidulans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43000
-
 gel filtration Aspergillus nidulans

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
-
 overview
-

Purification (Commentary)

Purification (Comment) Organism
-
 Aspergillus nidulans

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
14.9
-
-
 Aspergillus nidulans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
-
 Aspergillus nidulans 3-dehydroquinate + phosphate
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 43000, gel filtration Aspergillus nidulans

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Aspergillus nidulans