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Literature summary for 4.2.3.12 extracted from

  • Iwanaga, N.; Yamamasu, S.I.; Tachibana, D.; Nishio, J.; Nakai, Y.; Shintaku, H.; Ishiko, O.
    Activity of synthetic enzymes of tetrahydrobiopterin in the human placenta (2004), Int. J. Mol. Med., 13, 117-120.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7,8-dihydroneopterin triphosphate Homo sapiens
-
6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
chorion tissue from normal pregnant women Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.000611
-
during the third trimester, enzyme assays at 37°C and pH 7.4 Homo sapiens
0.000714
-
during the first trimester, enzyme assays at 37°C and pH 7.4 Homo sapiens
0.000782
-
during the second trimester, enzyme assays at 37°C and pH 7.4 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7,8-dihydroneopterin triphosphate
-
Homo sapiens 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate
-
?

Synonyms

Synonyms Comment Organism
6-pyruvoyltetrahydropterin synthase
-
Homo sapiens