Any feedback?
Literature summary for 4.2.1.51 extracted from
- Regulatory properties of prephenate dehydrogenase and prephenate dehydratase from Corynebacterium glutamicum (1974), Agric. Biol. Chem., 38, 2367-2376.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| 3-Aminotyrosine | activation | Corynebacterium glutamicum |  |
| D-tyrosine | activation | Corynebacterium glutamicum | |
| L-isoleucine | activation | Corynebacterium glutamicum | |
| L-leucine | activation | Corynebacterium glutamicum | |
| L-methionine | activation | Corynebacterium glutamicum | |
| L-tyrosine | activation | Corynebacterium glutamicum | |
| L-tyrosine | 1 mM, 6fold activation | Corynebacterium glutamicum | |
| p-aminophenylalanine | activation | Corynebacterium glutamicum | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-methyltryptophan | - |
Corynebacterium glutamicum | |
| 5-Methyltryptophan | - |
Corynebacterium glutamicum | |
| 6-Fluorotryptophan | - |
Corynebacterium glutamicum | |
| L-phenylalanine | 0.05 mM, 50% inhibition | Corynebacterium glutamicum | |
| L-tryptophan | 0.1 mM, 100% inhibition | Corynebacterium glutamicum | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.1 | - |
prephenate | - |
Corynebacterium glutamicum | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prephenate | Corynebacterium glutamicum | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Corynebacterium glutamicum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| prephenate | - |
Corynebacterium glutamicum | phenylpyruvate + H2O + CO2 | - |
? | |
| prephenate | - |
Corynebacterium glutamicum | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | 33 | - |
Corynebacterium glutamicum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.8 | - |
potassium phosphate buffer | Corynebacterium glutamicum |
| 7 | - |
,Tris-maleate buffer | Corynebacterium glutamicum |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.05 | - |
L-phenylalanine | - |
Corynebacterium glutamicum | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
