Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EDTA | inhibition can be alleviated by either Mn2+ or Co2+ | Klebsiella aerogenes | |
p-hydroxymercuribenzoate | on addition of glutathione or mercaptoethanol the activity is regained | Klebsiella aerogenes |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.15 | - |
2-keto-myo-inositol | - |
Klebsiella aerogenes |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | increases activity | Klebsiella aerogenes | |
Mn2+ | increases activity | Klebsiella aerogenes |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(2R,3S,4s,5R,6S)-2,3,4,5,6-pentahydroxycyclohexanone | Klebsiella aerogenes | pathway of myo-inositol degradation | (3R,4S,5R)-3,4,5-trihydroxycyclohexane-1,2-dione + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Klebsiella aerogenes | - |
- |
- |
Oxidation Stability | Organism |
---|---|
unstable when exposed to oxygen | Klebsiella aerogenes |
Purification (Comment) | Organism |
---|---|
partial | Klebsiella aerogenes |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
2,4,6/3,5-Pentahydroxycyclohexanone = 3,5/4-trihydroxycyclohexa-1,2-dione + H2O | mechanism | Klebsiella aerogenes |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
270 | - |
- |
Klebsiella aerogenes |
Storage Stability | Organism |
---|---|
-10°C, nitrogen atmosphere, for 1 month, about 50% loss of activity | Klebsiella aerogenes |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(2R,3S,4s,5R,6S)-2,3,4,5,6-pentahydroxycyclohexanone | - |
Klebsiella aerogenes | (3R,4S,5R)-3,4,5-trihydroxycyclohexane-1,2-dione + H2O | - |
? | |
(2R,3S,4s,5R,6S)-2,3,4,5,6-pentahydroxycyclohexanone | pathway of myo-inositol degradation | Klebsiella aerogenes | (3R,4S,5R)-3,4,5-trihydroxycyclohexane-1,2-dione + H2O | - |
? | |
L-2-Keto-epi-inositol | - |
Klebsiella aerogenes | ? | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6 | 6.2 | 2-keto-myo-inositol | Klebsiella aerogenes |