Literature summary for 4.2.1.28 extracted from

Schwartz, P.A.; Frey, P.A.
Dioldehydrase: an essential role for potassium ion in the homolytic cleavage of the cobalt-carbon bond in adenosylcobalamin (2007), Biochemistry, 46, 7293-7301.

Search for more literature for 4.2.1.28

Activating Compound

Activating Compound	Comment	Organism	Structure
oxygen	anaerobically no activity	Salmonella enterica subsp. enterica serovar Typhimurium

Cloned(Commentary)

Cloned (Comment)	Organism
expression vector pT7.7	Salmonella enterica subsp. enterica serovar Typhimurium

Metals/Ions

Metals/Ions	Comment	Organism	Structure
K+	-	Salmonella enterica subsp. enterica serovar Typhimurium

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
207000	-	molecular weight of hexamer	Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism	UniProt	Comment	Textmining
Salmonella enterica subsp. enterica serovar Typhimurium	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1,2-propanediol	-	Salmonella enterica subsp. enterica serovar Typhimurium	propionaldehyde + H2O	-	?

Subunits

Subunits	Comment	Organism
hexamer	dimer of heterotrimers, contained within the R-subunit is an (a/b) beta-barrel that houses the active site	Salmonella enterica subsp. enterica serovar Typhimurium

Synonyms

Synonyms	Comment	Organism
dioldehydrase	-	Salmonella enterica subsp. enterica serovar Typhimurium
DL-1,2-propanediol hydro-lyase	-	Salmonella enterica subsp. enterica serovar Typhimurium

Cofactor

Cofactor	Comment	Organism	Structure
adenosylcobalamin	-	Salmonella enterica subsp. enterica serovar Typhimurium

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Release 2023.1 (January 2023)