Literature summary for 4.2.1.24 extracted from

Petrovich, R.M.; Litwin, S.; Jaffe, E.K.
Bradyrhizobium japonicum porphobilinogen synthase uses two Mg(II) and monovalent cations (1996), J. Biol. Chem., 271, 8692-8699.

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Metals/Ions

Metals/Ions	Comment	Organism	Structure
K+	required	Bradyrhizobium japonicum
Mg2+	enzyme utilizes a catalytic MgA present at a stoichiometry of 4/octamer, an allosteric MgC present at a stoichiometry of 8/octamer and a monovalent metal ion, K+	Bradyrhizobium japonicum
Zinc	lacks a catalytic ZnA, enzyme can bind Zn(II), presumably as ZnA, at a stoichiometry of 4/octamer with a Kd of 0.2 mM, this high concentration is outside the physiologically significant range	Bradyrhizobium japonicum

Organism

Organism	UniProt	Comment	Textmining
Bradyrhizobium japonicum	-	-	-

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Release 2023.1 (January 2023)