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Literature summary for 4.2.1.22 extracted from

  • Bruintjes, J.J.; Henning, R.H.; Douwenga, W.; van der Zee, E.A.
    Hippocampal cystathionine beta synthase in young and aged mice (2014), Neurosci. Lett., 563, 135-139.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68000
-
x * 68000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-serine + L-homocysteine Mus musculus
-
L-cystathionine + H2O
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus
-
Mus musculus
-
liver
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-serine + L-homocysteine
-
Mus musculus L-cystathionine + H2O
-
?

Subunits

Subunits Comment Organism
? x * 68000, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
CBS
-
Mus musculus
cystathionine beta synthase
-
Mus musculus

Expression

Organism Comment Expression
Mus musculus mice at the unusual age of 28 months even have a higher hippocampal enzyme expression than young mice up

General Information

General Information Comment Organism
physiological function Cystathionine beta synthase (CBS) is the main contributor to the production of hydrogen sulfide (H2S) in the brain. The CBS/H2S pathway plays an important role in the protection of learning and memory functions in the brain at the level of the hippocampus Mus musculus