Literature summary for 4.2.1.22 extracted from

Ozaki, S.; Sakaguchi, C.; Nakahara, A.; Yoshiya, M.
Mutagenesis studies of human cystathionine beta-synthase: residues important for heme binding and substrate interactions (2010), Protein Pept. Lett., 17, 351-355.

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Protein Variants

Protein Variants	Comment	Organism
Q222X	mutagenesis studies reveal that Gln-222 is involved in interactions with substrates	Homo sapiens
R266X	mutagenesis studies reveal that Arg-266 is important to sense structural changes in heme-binding site	Homo sapiens
T223X	mutagenesis studies reveal that Tyr-223 is involved in interactions with substrates	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
CBS	-	Homo sapiens
cystathionine beta-synthase	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	-	Homo sapiens

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Release 2023.1 (January 2023)