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Literature summary for 4.2.1.22 extracted from

  • Hamelet, J.; Ait-Yahya-Graison, E.; Matulewicz, E.; Noll, C.; Badel-Chagnon, A.; Camproux, A.C.; Demuth, K.; Paul, J.L.; Delabar, J.M.; Janel, N.
    Homocysteine threshold value based on cystathionine beta synthase and paraoxonase 1 activities in mice (2007), Eur. J. Clin. Invest., 37, 933-938.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus hyperhomocysteinaemia is a metabolic disorder associated with the development of premature atherosclerosis. Cystathionine beta-synthase activity is significantly decreased in mice with a plasma homocysteine value greater than 0.015 mg ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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 moderate to intermediate murine model of hyperhomocysteinaemia. Using wild type and heterozygous cystathionine beta-synthase deficient mice fed a methionine enriched diet or a control diet
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Source Tissue

Source Tissue Comment Organism Textmining
blood hyperhomocysteinaemia is a metabolic disorder associated with the development of premature atherosclerosis. Cystathionine beta-synthase activity is significantly decreased in mice with a plasma homocysteine value greater than 0.015 mg Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information hyperhomocysteinaemia is a metabolic disorder associated with the development of premature atherosclerosis. Cystathionine beta-synthase activity is significantly decreased in mice with a plasma homocysteine value greater than 0.015 mg Mus musculus ?
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