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Literature summary for 4.2.1.22 extracted from

  • Kery, V.; Poneleit, L.; Meyer, J.D.; Manning, M.C.; Kraus, J.P.
    Binding of pyridoxal 5'-phosphate to the heme protein human cystathionine beta-synthase (1999), Biochemistry, 38, 2716-2724.
    View publication on PubMed
Search for more literature for 4.2.1.22

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Serine + homocysteine Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Serine + homocysteine
-
 Homo sapiens Cystathionine + H2O
-
 ?
L-Serine + homocysteine
-
 Homo sapiens ?
-
 ?

Cofactor

Cofactor Comment Organism Structure
heme 2 mol per mol of tetrameric enzyme Homo sapiens
pyridoxal 5'-phosphate Lys119 is eesential for the formation of the internal aldimine with pyridoxal 5'-phosphate Homo sapiens