Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(3S)-hydroxybutanoyl-CoA | competitive | Bos taurus | |
(3S)-hydroxyhexadecanoyl-CoA | competitive, 50% inhibition at 0.00075 mM, 90% inhibition by 0.004 mM | Bos taurus | |
3-ketohexadecanoyl-CoA | 0.008 mM, 40% inhibition | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.009 | - |
trans-2-hexadecenoyl-CoA | pH 8, 25°C | Bos taurus | |
0.022 | - |
crotonyl-CoA | pH 8, 25°C | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
crotonyl-CoA + H2O | - |
Bos taurus | (3S)-3-hydroxybutanoyl-CoA | - |
? | |
trans-2-decenoyl-CoA + H2O | Vmax is 8fold lower than with crotonyl-CoA | Bos taurus | (3S)-hydroxydecanoyl-CoA | - |
? | |
trans-2-hexadecenoyl-CoA + H2O | Vmax is 82fold lower than with crotonyl-CoA | Bos taurus | (3S)-hydroxyhexadecanoyl-CoA | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00035 | - |
(3S)-hydroxyhexadecanoyl-CoA | pH 8, 25°C | Bos taurus | |
0.037 | - |
(3S)-hydroxybutanoyl-CoA | pH 8, 25°C | Bos taurus |