Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.2.1.11 extracted from

  • Tovy, A.; Siman Tov, R.; Gaentzsch, R.; Helm, M.; Ankri, S.
    A new nuclear function of the Entamoeba histolytica glycolytic enzyme enolase: the metabolic regulation of cytosine-5 methyltransferase 2 (Dnmt2) activity (2010), PLoS Pathog., 6, e1000775.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Entamoeba histolytica 5737
-
nucleus
-
Entamoeba histolytica 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
47000
-
SDS-PAGE Entamoeba histolytica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-phospho-D-glycerate Entamoeba histolytica
-
phosphoenolpyruvate + H2O
-
r
additional information Entamoeba histolytica enolase acts as a DNA methyltransferase 2 inhibitor. Enolase interacts with Ehmeth, and modulates its activity under conditions of glucose starvation inhibiting the binding of Ehmeth and human DNA methyltransferase 2 to Entamoeba histolytica MRS2 DNA ?
-
?

Organism

Organism UniProt Comment Textmining
Entamoeba histolytica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phospho-D-glycerate
-
Entamoeba histolytica phosphoenolpyruvate + H2O
-
r
additional information enolase acts as a DNA methyltransferase 2 inhibitor. Enolase interacts with Ehmeth, and modulates its activity under conditions of glucose starvation inhibiting the binding of Ehmeth and human DNA methyltransferase 2 to Entamoeba histolytica MRS2 DNA Entamoeba histolytica ?
-
?

Synonyms

Synonyms Comment Organism
alpha-enolase
-
Entamoeba histolytica
enolase
-
Entamoeba histolytica