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Literature summary for 4.2.1.11 extracted from

  • Merkulova, T.; Lucas, M.; Jabet, C.; Lamande, N.; Rouzeau, J.D.; Gros, F.; Lazar, M.; Keller, A.
    Biochemical characterization of the mouse muscle-specific enolase: developmental changes in electrophoretic variants and selective binding to other proteins (1997), Biochem. J., 323, 791-800.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.1.11

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.078
-
 2-phospho-D-glycerate
-
 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-phospho-D-glycerate Mus musculus beta,beta-enolase binds with high affinity the adjacent enzymes in the glycolytic pathway (pyruvate kinase and phosphoglycerate mutase), beta,beta-enolase binds with high affinity sarcomeric troponin but not actin and tropomyosin ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
beta,beta-enolase Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
additional information the embryonic alpha,alpha isoform remains distributed in many adult cell types, wheras a transition towards beta,beta-isoform and gamma,gamma-isoform occurs in striated muscle cells and neurons respectively Mus musculus
-
muscle hindlimb muscle Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Mus musculus

Storage Stability

Storage Stability Organism
-74°C, pH 7.0, stable for up to 10 months, provided that multiple freezing and thawing steps are avoided Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phospho-D-glycerate
-
 Mus musculus phosphoenolpyruvate
-
 ?
2-phospho-D-glycerate beta,beta-enolase binds with high affinity the adjacent enzymes in the glycolytic pathway (pyruvate kinase and phosphoglycerate mutase), beta,beta-enolase binds with high affinity sarcomeric troponin but not actin and tropomyosin Mus musculus ?
-
 ?
2-phospho-D-glycerate
-
 Mus musculus phosphoenolpyruvate + H2O
-
 ?