Organism | UniProt | Comment | Textmining |
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Potorous tridactylus | - |
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Synonyms | Comment | Organism |
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CPD photolyase | - |
Potorous tridactylus |
General Information | Comment | Organism |
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malfunction | using transgenic mice expressing Potorous tridactylus CPD-photolyase, it is shown that Potorous CPD-photolyase affects the clock by shortening the period of behavioral rhythms. Constitutively expressed CPD-photolyase is shown to reduce the amplitude of circadian oscillations in cultured cells and to inhibit CLOCK/BMAL1 driven transcription by interacting with CLOCK. Potorous CPD-photolyase can restore the molecular oscillator in the liver of (clock-deficient) Cry1/Cry2 double knockout mice | Potorous tridactylus |