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Literature summary for 4.1.99.3 extracted from

  • Byrdin, M.; Villette, S.; Espagne, A.; Eker, A.P.; Brettel, K.
    Polarized transient absorption to resolve electron transfer between tryptophans in DNA photolyase (2008), J. Phys. Chem. B, 112, 6866-6871.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
W306F in the W306F mutant, the terminal tryptophan W306 is replaced by an isosteric phenylalanine that is much harder to oxidize, thus leaving the electron-transfer chain cut off after the second tryptophan W359, the W359 radical formed in the W306F mutant photolyase is in its neutral form already at 10 ns after excitation Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
54000
-
roughly estimated molecular weight Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P00914
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclobutadipyrimidine in DNA
-
Escherichia coli pyrimidine residues in DNA
-
?

Synonyms

Synonyms Comment Organism
DNA photolyase
-
Escherichia coli

Cofactor

Cofactor Comment Organism Structure
FAD the repair reaction involves electron transfer to the cyclobutane pyrimidine dimers from the photoexcited FAD cofactor in its fully reduced form Escherichia coli