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Literature summary for 4.1.99.3 extracted from

  • Yang, K.; Matsika, S.; Stanley, R.J.
    6MAP, a fluorescent adenine analogue, is a probe of base flipping by DNA photolyase (2007), J. Phys. Chem. B, 111, 10615-10625.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
cloned in Escherichia coli Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclobutadipyrimidine in DNA
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Escherichia coli 2 pyrimidine residues in DNA
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?
additional information 4-amino-6-methyl-8-(2'-deoxy-beta-D-ribofuranosyl)-7(8H)-pteridone (6MAP) is a fluorescent adenine analogue that demonstrates high sensitivity to base-stacking interactions in duplex DNA. 6MAP is a sensitive probe of cyclobutylpyrimidine dimers base flipping by photolyase and does does not interfere with the repair of the substrate. It is shown that 6MAP/cyclobutylpyrimidine dimers duplexes are true substrates of photolyase Escherichia coli ?
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?

Synonyms

Synonyms Comment Organism
DNA photolyase
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Escherichia coli