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Literature summary for 4.1.99.17 extracted from

  • Dougherty, M.J.; Downs, D.M.
    A connection between iron-sulfur cluster metabolism and the biosynthesis of 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate in Salmonella enterica (2006), Microbiology, 152, 2345-2353.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
4Fe-4S cluster
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Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium Q9L9I7
-
-

Oxidation Stability

Oxidation Stability Organism
identification of variants of ThiC that have increased sensitivity to oxidative growth conditions Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-amino-1-(5-phospho-D-ribosyl)imidazole + S-adenosyl-L-methionine
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Salmonella enterica subsp. enterica serovar Typhimurium 4-amino-2-methyl-5-phosphomethylpyrimidine + 5'-deoxyadenosine + L-methionine + formate + CO
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