Literature summary for 4.1.3.3 extracted from

Huang, S.; Yu, H.; Chen, X.
Disaccharides as sialic acid aldolase substrates: Synthesis of disaccharides containing a sialic acid at the reducing end (2007), Angew. Chem. Int. Ed. Engl., 46, 2249-2253.

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Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
Bio-Gel P-2 gel filtration	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-deoxy-2-[[(alpha-D-galactopyranosyloxy)acetyl]amino]-D-mannopyranose + pyruvate	-	Escherichia coli	3,5-dideoxy-5-[[(alpha-D-galactopyranosyloxy)acetyl]amino]-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	36% yield	?
2-deoxy-2-[[(beta-D-galactopyranosyloxy)acetyl]amino]-D-mannopyranose + pyruvate	-	Escherichia coli	3,5-dideoxy-5-[[(beta-D-galactopyranosyloxy)acetyl]amino]-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	34% yield	?
4-O-alpha-D-galactopyranosyl-D-mannopyranose + pyruvate	-	Escherichia coli	3-deoxy-7-O-alpha-D-galactopyranosyl-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	5% yield	?
4-O-beta-D-galactopyranosyl-D-mannopyranose + pyruvate	-	Escherichia coli	3-deoxy-7-O-beta-D-galactopyranosyl-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	38% yield	?
4-O-beta-D-glucopyranosyl-D-mannopyranose + pyruvate	-	Escherichia coli	3-deoxy-7-O-beta-D-glucopyranosyl-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	35% yield	?
5-O-alpha-D-galactopyranosyl-alpha-D-mannofuranose + pyruvate	-	Escherichia coli	3-deoxy-8-O-alpha-D-galactopyranosyl-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	62% yield	?
5-O-beta-D-galactopyranosyl-alpha-D-mannofuranose + pyruvate	-	Escherichia coli	3-deoxy-8-O-beta-D-galactopyranosyl-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	85% yield	?
6-O-alpha-D-galactopyranosyl-D-mannopyranose + pyruvate	-	Escherichia coli	3-deoxy-9-O-alpha-D-galactopyranosyl-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	81% yield	?
6-O-alpha-D-glucopyranosyl-D-mannopyranose + pyruvate	-	Escherichia coli	3-deoxy-9-O-alpha-D-glucopyranosyl-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	65% yield	?
6-O-alpha-D-mannopyranosyl-D-mannopyranose + pyruvate	-	Escherichia coli	3-deoxy-9-O-alpha-D-mannopyranosyl-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	78% yield	?
6-O-beta-D-glucopyranosyl-D-mannopyranose + pyruvate	-	Escherichia coli	3-deoxy-9-O-beta-D-glucopyranosyl-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid	83% yield	?
N-acetyl-neuraminic acid	-	Escherichia coli	N-acetyl-D-mannosamine + pyruvate	-	r

Synonyms

Synonyms	Comment	Organism
NAL	-	Escherichia coli
Neu5Ac lyase	-	Escherichia coli
Sialic acid aldolase	-	Escherichia coli

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Release 2023.1 (January 2023)