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Literature summary for 4.1.3.27 extracted from

  • Robb, F.; Hutchinson, M.A.; Belser, W.L.
    Anthranilate synthetase. Some physical and kinetic properties of the enzyme from Serratia marcescens (1971), J. Biol. Chem., 246, 6908-6912.
    View publication on PubMed
Search for more literature for 4.1.3.27

Inhibitors

Inhibitors Comment Organism Structure
L-Trp feedback inhibition Serratia marcescens
PCMB
-
 Serratia marcescens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0031
-
 chorismate
-
 Serratia marcescens
0.33
-
 Gln
-
 Serratia marcescens
10
-
 NH4+
-
 Serratia marcescens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
140000
-
 sucrose density gradient centrifugation Serratia marcescens
150000
-
 gel filtration Serratia marcescens

Organism

Organism UniProt Comment Textmining
Serratia marcescens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Serratia marcescens

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.5
-
-
 Serratia marcescens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chorismate + L-Gln
-
 Serratia marcescens anthranilate + pyruvate + L-glutamate
-
 ?
chorismate + NH4+
-
 Serratia marcescens ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
 Gln-dependent activity Serratia marcescens
8.5
-
 above pH 8.5 Serratia marcescens

pH Range

pH Minimum pH Maximum Comment Organism
6 8 about 75% of maximal activity, Gln-dependent activity Serratia marcescens