Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(NH4)2SO4 | 50% inhibition at 2.1 mM at 37°C, 50% inhibition at 1.9 mM at 5°C | Callospermophilus lateralis | |
(NH4)2SO4 | 50% inhibition at 6.2 mM at 37°C, 50% inhibition at 5.27 mM at 5°C | Oryctolagus cuniculus | |
ADP | 50% inhibition at 1.6 mM at 37°C, 50% inhibition at 1.7 mM at 5°C | Callospermophilus lateralis | |
ADP | 50% inhibition at 2.7 mM at 37°C, 50% inhibition at 5.4 mM at 5°C | Oryctolagus cuniculus | |
AMP | 50% inhibition at 2.3 mM at 37°C, 50% inhibition at 2.6 mM at 5°C | Callospermophilus lateralis | |
AMP | 50% inhibition at 4.5 mM at 37°C, 50% inhibition at 6.0 mM at 5°C | Oryctolagus cuniculus | |
ATP | 50% inhibition at 1.4 mM at 37°C, 50% inhibition at 1.1 mM at 5°C | Callospermophilus lateralis | |
ATP | 50% inhibition at 2.1 mM at 37°C, 50% inhibition at 2.1 mM at 5°C | Oryctolagus cuniculus | |
citrate | 50% inhibition at 2.4 mM at 37°C, 50% inhibition at 1.9 mM at 5°C | Callospermophilus lateralis | |
citrate | 50% inhibition at 2.7 mM at 37°C, 50% inhibition at 3.4 mM at 5°C | Oryctolagus cuniculus | |
IMP | 50% inhibition at 1.3 mM at 37°C, 50% inhibition at 1.3 mM at 5°C | Callospermophilus lateralis | |
IMP | 50% inhibition at 4.2 mM at 37°C, 50% inhibition at 8.5 mM at 5°C | Oryctolagus cuniculus | |
KCl | 50% inhibition at 38.2 mM at 37°C, 50% inhibition at 36.1 mM at 5°C | Callospermophilus lateralis | |
KCl | 50% inhibition at 111 mM at 37°C, 50% inhibition at 63.3 mM at 5°C | Oryctolagus cuniculus | |
Magnesium citrate | 50% inhibition at 1.9 mM at 37°C, 50% inhibition at 2.5 mM at 5°C | Callospermophilus lateralis | |
Magnesium citrate | 50% inhibition at 9 mM at 37°C, 50% inhibition at 2.5 mM at 5°C | Oryctolagus cuniculus | |
NaCl | 50% inhibition at 14.7 mM at 37°C, 50% inhibition at 31 mM at 5°C | Callospermophilus lateralis | |
NaCl | 50% inhibition at 110 mM at 37°C, 50% inhibition at 52 mM at 5°C | Oryctolagus cuniculus | |
NH4Cl | 50% inhibition at 51.5 mM at 37°C, 50% inhibition at 34.1 mM at 5°C | Callospermophilus lateralis | |
NH4Cl | 50% inhibition at 166 mM at 37°C, 50% inhibition at 40.6 mM at 5°C | Oryctolagus cuniculus | |
phosphate | 50% inhibition at 1.7 mM at 37°C, 50% inhibition at 0.63 mM at 5°C | Callospermophilus lateralis | |
phosphate | 50% inhibition at 6.1 mM at 37°C, 50% inhibition at 1.7 mM at 5°C | Oryctolagus cuniculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0009 | - |
D-fructose 1,6-bisphosphate | pH 7.3, 37°C | Callospermophilus lateralis | |
0.0013 | - |
D-fructose 1,6-bisphosphate | pH 7.3, 37°C | Oryctolagus cuniculus | |
0.00145 | - |
D-fructose 1,6-bisphosphate | pH 7.3, 5°C | Callospermophilus lateralis | |
0.00411 | - |
D-fructose 1,6-bisphosphate | pH 7.3, 5°C | Oryctolagus cuniculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
4 * 40000, SDS-PAGE | Callospermophilus lateralis |
159000 | - |
gel filtration | Callospermophilus lateralis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-fructose 1,6-bisphosphate | Oryctolagus cuniculus | - |
glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
r | |
D-fructose 1,6-bisphosphate | Callospermophilus lateralis | - |
glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Callospermophilus lateralis | - |
golden-mantled ground squirrel | - |
Oryctolagus cuniculus | - |
rabbit | - |
Purification (Comment) | Organism |
---|---|
homogeneity | Callospermophilus lateralis |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
Callospermophilus lateralis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-fructose 1,6-bisphosphate | - |
Oryctolagus cuniculus | glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
r | |
D-fructose 1,6-bisphosphate | - |
Callospermophilus lateralis | glycerone phosphate + D-glyceraldehyde 3-phosphate | - |
r |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 40000, SDS-PAGE | Callospermophilus lateralis |
Synonyms | Comment | Organism |
---|---|---|
F1,6P2 aldolase | - |
Callospermophilus lateralis |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.3 | 7.5 | - |
Callospermophilus lateralis |
7 | - |
- |
Oryctolagus cuniculus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
steep drop in activity above | Callospermophilus lateralis |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00023 | - |
phosphate | pH 7.3, 5°C | Callospermophilus lateralis | |
0.00118 | - |
phosphate | pH 7.3, 37°C | Callospermophilus lateralis |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Callospermophilus lateralis | isoelectric focusing, pH gradient pH 3.5 - pH 10 | - |
5.5 |