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Literature summary for 4.1.1.65 extracted from

  • Horvath, S.E.; Boettinger, L.; Voegtle, F.N.; Wiedemann, N.; Meisinger, C.; Becker, T.; Daum, G.
    Processing and topology of the yeast mitochondrial phosphatidylserine decarboxylase 1 (2012), J. Biol. Chem., 287, 36744-36755.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.1.65

Protein Variants

Protein Variants Comment Organism
S463A the mutant does not display detectable decarboxylase activity due to the inability to generate the active site of the enzyme Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion the enzyme requires integration into the inner mitochondrial membrane for full enzymatic activity Saccharomyces cerevisiae 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
10000
-
 1 * 45000 + 1 * 10000, SDS-PAGE Saccharomyces cerevisiae
45000
-
 1 * 45000 + 1 * 10000, SDS-PAGE Saccharomyces cerevisiae
55000
-
 gel filtration Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Phosphatidyl-L-serine Saccharomyces cerevisiae
-
 Phosphatidylethanolamine + CO2
-
 ?
Phosphatidyl-L-serine Saccharomyces cerevisiae BY4741
-
 Phosphatidylethanolamine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae BY4741
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Phosphatidyl-L-serine
-
 Saccharomyces cerevisiae Phosphatidylethanolamine + CO2
-
 ?
Phosphatidyl-L-serine
-
 Saccharomyces cerevisiae BY4741 Phosphatidylethanolamine + CO2
-
 ?

Subunits

Subunits Comment Organism
heterodimer 1 * 45000 + 1 * 10000, SDS-PAGE Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
phosphatidylserine decarboxylase 1
-
 Saccharomyces cerevisiae
PSD1
-
 Saccharomyces cerevisiae