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Literature summary for 4.1.1.65 extracted from

  • Wriessnegger, T.; Sunga, A.J.; Cregg, J.M.; Daum, G.
    Identification of phosphatidylserine decarboxylases 1 and 2 from Pichia pastoris (2009), FEMS Yeast Res., 9, 911-922.
    View publication on PubMed
Search for more literature for 4.1.1.65

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion isoform PSD1 Komagataella pastoris 5739
-

Organism

Organism UniProt Comment Textmining
Komagataella pastoris
-
-
-
Komagataella pastoris GS115
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Phosphatidyl-L-serine
-
 Komagataella pastoris Phosphatidylethanolamine + CO2
-
 ?
Phosphatidyl-L-serine
-
 Komagataella pastoris GS115 Phosphatidylethanolamine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
PSD1 isoform Komagataella pastoris
Psd1p isoform Komagataella pastoris
PSD2 isoform Komagataella pastoris
Psd2p isoform Komagataella pastoris

General Information

General Information Comment Organism
malfunction deletion of isoform PSD1 causes loss of PSD activity in mitochondria, a severe growth defect on minimal media, and depletion of cellular and mitochondrial phosphatidylethanolamine levels. This defect cannot be compensated by Psd2p. In the homogenate of psd2DELTA, the PSD activity is only slightly reduced, whereas in psd1DELTA total PSD activity is only 25% of wild type Komagataella pastoris