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Literature summary for 4.1.1.65 extracted from
- Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae (2004), Biochim. Biophys. Acta, 1686, 161-168.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | phosphatidylserine decarboxylase 2 | Saccharomyces cerevisiae | 5794 | - |
| mitochondrial membrane | phosphatidylserine decarboxylase 1 | Saccharomyces cerevisiae | 31966 | - |
| vacuole | phosphatidylserine decarboxylase 2 | Saccharomyces cerevisiae | 5773 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Phosphatidyl-L-serine | Saccharomyces cerevisiae | phosphatidylethanolamine formed by phosphatidylserine decarboxylase 2 is the preferred substrate for phosphatidylcholine synthesis, phosphatidylethanolamine formed by phosphatidylserine decarboxylase 2 can be imported into mitochondria, although with moderate efficiency | Phosphatidylethanolamine + CO2 | - |
? |  |
| Phosphatidyl-L-serine | Saccharomyces cerevisiae | phosphatidylserine decarboxylase 1 is the major source of cellular and mitochondrial phosphatidylethanolamine | Phosphatidylethanolamine + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Phosphatidyl-L-serine | - |
Saccharomyces cerevisiae | Phosphatidylethanolamine + CO2 | - |
? | |
| Phosphatidyl-L-serine | phosphatidylethanolamine formed by phosphatidylserine decarboxylase 2 is the preferred substrate for phosphatidylcholine synthesis, phosphatidylethanolamine formed by phosphatidylserine decarboxylase 2 can be imported into mitochondria, although with moderate efficiency | Saccharomyces cerevisiae | Phosphatidylethanolamine + CO2 | - |
? | |
| Phosphatidyl-L-serine | phosphatidylserine decarboxylase 1 is the major source of cellular and mitochondrial phosphatidylethanolamine | Saccharomyces cerevisiae | Phosphatidylethanolamine + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| phosphatidylserine decarboxylase 1 | - |
Saccharomyces cerevisiae |
| phosphatidylserine decarboxylase 2 | - |
Saccharomyces cerevisiae |
| Psd1p | - |
Saccharomyces cerevisiae |
| Psd2p | - |
Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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