Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 (DE3) cells | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4'-phosphopantothenol | - |
Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA metal-affinity column chromatography | Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-[(R)-4'-phosphopantothenoyl]-L-cysteine | - |
Mycobacterium tuberculosis | pantotheine 4'-phosphate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
4'-phosphopantothenoylcysteine decarboxylase | - |
Mycobacterium tuberculosis |
CoaBC | - |
Mycobacterium tuberculosis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
flavin | - |
Mycobacterium tuberculosis |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.063 | - |
in 50 mM Tris, 0.2 mM cysteine, 0.2 mM CTP, 0.2 mM dithiothreitol, 0.2 mM MgCl2, at 37°C | Mycobacterium tuberculosis | 4'-phosphopantothenol |