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Literature summary for 4.1.1.36 extracted from

  • Abiko, Y.
    Investigations on pantothenic acid and its related compounds (1967), J. Biochem., 61, 300-308.
    View publication on PubMed
Search for more literature for 4.1.1.36

Inhibitors

Inhibitors Comment Organism Structure
ATP reversed by equimolar amount of semicarbazide Rattus norvegicus
additional information no effect of ADP and AMP Rattus norvegicus
pantotheine 4-phosphate competitive product inhibition Rattus norvegicus
pyridoxal reversed by equimolar amount of semicarbazide Rattus norvegicus
pyridoxal 5'-phosphate reversed by equimolar amount of semicarbazide Rattus norvegicus
UTP reversed by equimolar amount of semicarbazide Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.133 0.15 phosphopantothenoyl-L-Cys
-
 Rattus norvegicus

Metals/Ions

Metals/Ions Comment Organism Structure
additional information Mg2+ has no effect Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.03
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information pantothenylcysteine is decarboxylated Rattus norvegicus ?
-
 ?
N-((R)-4-Phosphopantothenoyl)-L-Cys
-
 Rattus norvegicus Pantotheine 4-phosphate + CO2
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Rattus norvegicus