Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3,3-dichloro-2-(dihydroxyphosphinoylmethyl) propenoate | micromolar inhibitor | Plasmodium falciparum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoenolpyruvate + HCO3- | Plasmodium falciparum | - |
phosphate + oxaloacetate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium falciparum | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoenolpyruvate + HCO3- | - |
Plasmodium falciparum | phosphate + oxaloacetate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PEPC | - |
Plasmodium falciparum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
acetyl-CoA | - |
Plasmodium falciparum |
General Information | Comment | Organism |
---|---|---|
malfunction | an enzyme-deficient mutant shows severe growth defect in vitro | Plasmodium falciparum |
metabolism | the enzyme has a key role in carbon metabolism by fixing CO2 | Plasmodium falciparum |
physiological function | the phosphoenolpyruvate carboxylase gene is important for intra-erythrocytic survival of Plasmodium falciparum | Plasmodium falciparum |